Unify Design, Editing & Cell Line Development in One Platform

Accelerate discovery with an integrated platform purpose-built for molecular biology. From construct design and oligo synthesis to gene editing and cell line generation, Dotmatics helps you plan, execute, and optimize your entire workflow, without switching tools or losing data.

Get a demo of Dotmatics for Gene & Cell Engineering.

Trusted by the world's leading scientific organizations

Powerful Tools for Every Step of the Gene & Cell Engineering Workflow

From construct design to stable cell lines, Dotmatics connects your entire workflow with intelligent automation, scientific flexibility, and full traceability.

Precise Construct Design Tools

Design and annotate DNA constructs, validate sequences, and streamline vector or protein design with intuitive, integrated tools.

Oligo Synthesis Management

Automatically generate, register, and manage primers, gRNAs, and donor templates, linking design to action seamlessly. entire cloning pipeline.

Gene Editing Workflows

Design and execute CRISPR or other editing approaches with guide RNA support, batch tracking, and integrated screening.

Cell Line Development

Manage clone tracking, expression screening, and lineage relationships to optimize selection and scale-up.

Real-Time Workflow Traceability

Follow every construct, edit, and cell lineage through connected, auditable workflows, all in one environment.

Adaptive Workflow Automation

Configure and scale low-code workflows to match your lab’s evolving needs, from design to expression-ready lines.

Why Dotmatics for Gene & Cell Engineering?

Dotmatics brings your full molecular biology workflow into one connected platform, eliminating the need for siloed tools and fragmented data. With built-in automation, scientists reduce manual tasks and improve data traceability, reproducibility, and decision-making across experiments.

Frequently Asked Questions

How Leading Teams Use Dotmatics

Use Case: A biotech team edits CHO cells using CRISPR and uses Dotmatics to manage guide design, edits, and clone screening across iterations.

Precision Cell Line Engineering

Use Case: A research group designs and synthesizes primers and donor templates, seamlessly managing sequence data and vendor orders through Dotmatics.

Oligo Design & Synthesis

Use Case: A pharma team designs guide RNAs, performs editing, and advances stable clones for protein production, all within one platform.

End-to-End Editing Workflow

The Platform Molecular Biologists Actually Want to Use.

Designed with scientists in mind, the platform combines an intuitive interface with deep technical capabilities, making it easy to manage complex molecular biology workflows. Built to scale, secure, and robust enough to support high-throughput labs and enterprise-level deployments.

Get a demo of Dotmatics for Gene & Cell Engineering

Learn how you can use Dotmatics to accelerate scientific innovation across molecular biology.