Dotmatics ELN | The Electronic Lab Notebook Built for R&D Teams
Enterprise ELN

The Flexible ELN Built for
How Scientists Actually Work

Dotmatics ELN is the all-in-one platform that helps R&D teams digitize their labs, cut documentation time by up to 70%, and reach innovation targets faster. Flexible templating that adapts to your workflows, not the other way around.

2M+ leading scientists trust us
125 countries
ISO 9001 & 27001 certified

See Dotmatics ELN in Action

Talk to a scientist on our team. No pressure, no script, just a real look at the platform.

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Trusted by the world's leading scientific organizations

70%
Less time on manual lab documentation
Our flexible templating and simple framework help scientists reclaim time from documentation and spend it on discovery.
3x
Faster experiment search vs. paper notebooks
Full-text, structure, and metadata search across every experiment, notebook, and result, not just the ones you remember to tag.
100%
Audit-ready from day one
Electronic signatures, immutable audit trails, and Part 11-ready controls are built in, so compliance doesn't slow your science down.

All-in-one ELN software built for flexible, modern labs

Flexible templating, simple data capture, and structured search across every experiment type. Trusted by leading scientists across 125 countries to digitize their labs and reach innovation targets faster.

Flexible Templating, Not Rigid Forms
Capture any experiment type in a configurable canvas. Tables, chemical structures, images, sketches, spectra — exactly how your scientists want to work, not how IT configured a template three years ago.
Templates That Actually Scale
Standardize repeatable methods with protocol templates and structured fields. Build once, deploy across every team, and version-control everything so nothing gets lost when someone leaves.
Native Scientific Data Types
Molecules, reactions, sequences, images, spectra, and dose-response curves are first-class citizens. No workarounds, no attaching PDFs — data stays FAIR, searchable, and reusable.
Search Anything, Find It Fast
Full-text and structure search across every experiment, sample, result, and notebook. Permalinks let you share exact results with teammates in seconds instead of hunting through folders.
Integrated with Your Stack
Connect directly to registration, Prism, Luma Lab Connect, inventory, and third-party instruments. Open APIs let you route data to your data warehouse or BI layer without custom dev work.
Collaboration Without Friction
Real-time sharing across internal teams, sites, and external CRO partners. Granular permissions keep your IP protected while giving collaborators exactly the access they need and nothing more.
Inventory and Registration Built In
Track samples, compounds, plasmids, and reagents alongside your experiments. Full traceability from raw material to formulated product, with lineage you can actually audit.
Multi-Experiment Workflows
New in 7.5: build hierarchical experiment networks where precursors feed downstream experiments. Visualize your entire process capture workflow in one place, across any protocol type.
Security That Meets Regulated Environments
AES-256 encryption, TLS 1.2 in transit, role-based access, full audit trails, and electronic signature support. ISO 9001 and 27001 certified. Part 11-ready and GAMP 5 aligned.
Agent Luma — AI That Works on Your Actual Data
Luma Lab Connect
Luma Lab Connect weaves structured AI throughout your ELN. Ask Agent Luma natural language questions across multi-table datasets, generate first-pass experimental write-ups automatically, and build data applications from screening files in days instead of weeks. Because Luma data is structured from the start, the AI doesn't guess — it reasons from your actual scientific record.

See how leading scientists digitize their labs

Dotmatics ELN lets research teams jump-start their discovery journey with flexible templates, all-in-one data capture, and real-time insights. See why leading scientists around the world trust Dotmatics to reach innovation targets faster.

Single-click cell editing in Canvas tables, Excel-like keyboard navigation
Preserved column settings per experiment, per user
Consistent chemical structure rendering across all workflows
Multi-experiment hierarchy with genealogy tracking
Agent Luma generates experimental write-ups, answers natural language queries against your data, and identifies synthesis facts your ELN didn't explicitly record
Closed-loop screening workflows: an ELN request triggers screening, instrument results are parsed and returned automatically, so scientists spend time interpreting, not formatting
Book a Demo G2 Leader — Electronic Lab Notebook
Screening curve fit
ELN screening curve fit experiment 1
ELN reaction workflows
Dotmatics ELN screenshot
Dotmatics ELN screenshot
Dotmatics ELN screenshot
Dotmatics ELN screenshot
Agent Luma
Luma Lab Connect

The AI layer that actually shows its work

Agent Luma is woven throughout the ELN and the broader platform. Unlike general-purpose AI tools making educated guesses from unstructured text, Luma operates on data that is structured from the start — which means it has less to infer and more to work with directly. Traceable, explainable, and verifiable, because science requires auditability in a way most industries don’t.

Natural language queries
Ask a question in plain English against your actual multi-table dataset. Luma surfaces results, flags clinical significance, and suggests next experiments — no SQL, no export required.
AI-generated write-ups
Raw chemistry data in. Structured write-up out. Luma identifies the reaction type, flags a 43% yield as below-threshold, and questions the solvent — without being prompted to look for any of it.
App-building from screening files
Describe the objective, upload screening files. Luma builds the data model, writes the table structure, and generates data flows — configuration work that typically takes weeks, done in days.

The value isn’t just automation. It’s that the AI is operating on your actual scientific data, not generating plausible-sounding content around gaps in it.

Simple, hosted, and built for regulated science

Dotmatics ELN meets the security and compliance bar for pharma, biotech, and regulated research organizations from day one.

ISO 9001:2015 and ISO 27001:2022 certified
FDA 21 CFR Part 11 compliant electronic records and signatures
GAMP 5 aligned, supporting GxP environments with dedicated expert support
GDPR compliant with data residency options
AES-256 encryption at rest, TLS 1.2 in transit
Immutable audit trails and comprehensive access controls
ISO Certification ISO 9001:2015 Quality Management System
ISO 27001 ISO 27001:2022 Information Security Management
Data security GAMP 5 Aligned Quality & security by design
FDA 21 CFR Part 11 Electronic records & signatures

See the all-in-one ELN in action

Watch how research teams jump-start their discovery journey — from flexible experiment capture to searchable, analyzable data — all in one place.

Get a Personalized Demo

Trusted by leading scientists worldwide

From early-stage biotech to global pharma, Dotmatics helps teams reach innovation targets faster.

Read Dotmatics reviews on G2

"With the previous process it easily took an hour to analyze a single simple experiment. Now it takes less than ten minutes. Previously we analyzed all the data in Excel files, which was extremely hands on, took a long time, and had a lot of risk of error. Now there's an efficiency in terms of time but, more importantly for us, an improvement in quality, reproducibility, and consistency."

Antabio

"Our power users built the system together with the Dotmatics experts, which made it their solution. This contributed to the fact that they were very open to the new system and had a positive attitude towards it. One of the biggest unexpected consequences we've seen is that it saves scientists hours of time spent analyzing data."

Merck KGaA

"Dotmatics has transformed our R&D processes by providing an integrated, cloud-based platform that meets the diverse needs of our multidisciplinary teams. The transition has significantly improved our data management, streamlined our workflows, and enhanced internal communication. We've seen a notable increase in user engagement, reflecting the platform's positive impact on our research and decision-making capabilities."

Bial

Common questions

Things R&D leaders and IT teams at leading science organizations typically ask before a demo.

Dotmatics ELN is built for multi-disciplinary science. It supports synthetic and analytical chemistry, molecular biology, screening, formulation and process capture, biologics workflows, materials science, and custom experiment types. The same platform handles early discovery notebooks and regulated manufacturing workflows, so your teams don't need separate tools as science matures.
Dotmatics ELN connects natively to compound registration, BioRegister, inventory, screening, data discovery, and Prism within the Dotmatics platform. For third-party systems, the open REST API lets you route data to your data warehouse, LIMS, or BI layer. The 7.5 release also includes direct instrument file linking via Luma Lab Connect, reducing manual data entry across your stack.
Our implementation team works directly with your scientists and IT to build protocol templates that match your existing workflows, not generic ones that need to be retrofit. Most organizations are capturing experiments in the system within the first few weeks. We involve end users early, which is why adoption rates are high. Dotmatics employees are also industry scientists, so they can support your GxP integrations and specific scientific needs directly.
Dotmatics ELN supports real-time data sharing across internal teams, geographic sites, and external CRO partners, all from one instance. Granular, role-based access controls let you give collaborators exactly the access they need while keeping your IP protected. Permalinks make sharing a specific experiment result or notebook as simple as copying a link.
Yes. Dotmatics ELN is built in alignment with GAMP 5 guidelines and supports integration into GLP and GMP environments. The platform includes FDA 21 CFR Part 11 compliant electronic records and signatures, comprehensive audit trails, ISO 9001:2015 and ISO 27001:2022 certifications, and GDPR compliance. Our team includes industry experts who can support your GxP validation and compliance requirements directly.
Version 7.5 brings several meaningful ELN improvements: multi-experiment workflow support is no longer restricted to formulation protocol types, Canvas tables now have Excel-like keyboard navigation and persistent column settings, per-experiment properties can be added across multiple protocols at once, and chemical structure rendering is now consistent across reaction workflows and the ELN. Data discovery also gained conditional formatting in pivot views and cleaner Excel exports. If you're currently on an older version or evaluating competitors, 7.5 closes several gaps.
Jump-Start Your Lab's Discovery Journey

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See why leading scientists around the world trust Dotmatics ELN to digitize their labs, save up to 70% of documentation time, and reach innovation targets faster.

No commitment, no sales pressure
Shown by someone who understands your science
Tailored to your lab’s specific workflows