Trusted by the world's leading scientific organizations
Accelerate discovery with an integrated platform purpose-built for molecular biology. From gene cloning and protein expression to downstream purification, Dotmatics helps you design, manage, and optimize your entire workflow, without switching tools or losing data.
Get a demo of Dotmatics for Cloning, Expression & Purification.
From construct design to protein purification, Dotmatics connects your entire workflow with intelligent automation, real-time insights, and scientific flexibility built to scale.
Design and annotate DNA constructs, validate sequences, and streamline primer design with with intuitive tools built for molecular cloning workflows.
Eliminate manual steps by automating vector registration, sequence linking, and batch creation across your entire cloning pipeline.
Build and register high-performance expression vectors, including co-expression groups for complex proteins like antibodies and multispecifics.
Define expression conditions, manage experiments, and track production data across bacterial, yeast, or mammalian cell systems.
Plan and execute purification worflows, validate results, and register purified batches with structured data and full traceability.
Combine assay data like ELISA or FabTm with sequence and expression info to visualize protein quality and yield in real time.
Follow every construct, experiment, and result through connected, auditable workflows - all in one centralized data environment.
Move faster from design to discovery with tools built to optimize protein stability, expression, and collaboration across teams.
Connect every stage of biologics development - from annotated sequences to purified protein with traceable end-to-end data and workflow integration.
Dotmatics brings your entire cloning, expression, and purification workflow into one connected platform, eliminating the need for siloed tools and fragmented data. With built-in automation, scientists can reduce manual errors and repetitive tasks, improving both speed and consistency across experiments.
Use Case: A biotech team designs and expresses monoclonal antibody variants in CHO cells, using Dotmatics to track cloning, expression, and purification data to identify high-affinity candidates faster.
Therapeutic Antibody Development
Use Case: Scientists engineer enzyme variants for improved stability, using Dotmatics to manage mutagenesis, expression in E. coli, and purification results across multiple design cycles.
Enzyme Optimization for Biocatalysis
Use Case: A pharma team clones and expresses a synaptic protein in HEK cells for binding studies, using Dotmatics to coordinate construct design, protein expression, and purification workflows across teams.
Target Validation in Drug Discovery
Designed with scientists in mind, the platform combines an intuitive interface with deep technical capabilities, making it easy to manage complex molecular biology workflows. It's also built to scale, secure and robust enough to support high-throughput labs and enterprise-level deployments.
Learn how you can use Dotmatics to accelerate scientific innovation.